Pathophysiology & Microbiology

August 11, 2015

General Information
Duration 1 semester (14 teaching weeks)
Level Year 2, Semester 4
Unit Weighting Unit Credit Points: 10 credit points
Total Course Credit Points: 320 credit points
Student Workload Number of timetabled hours per week: 4
Number of personal study hours per week: 6
Total workload hours per week:10
Prerequisites/ Corequisites HMS201 Pathology
Academic Details
Description The first part of this unit addresses patho-physiological change and clinical manifestation of disorders of water and electrolyte metabolism, disorders of acid-base balance, shock, disorders of coagulation and anticoagulation balance, ischemia-reperfusion injury, pulmonary pathophysiology, cardiovascular dysfunction, hepatic pathophysiology and renal dysfunction.

The other part of this unit introduces students to Microbiology. Students will firstly study the nature and types of microorganisms including bacteria, fungi, viruses and protozoa. The topics address their structure, physiology, growth, diversity, inter-relationship and control mechanisms. Emphasis of this study will be on the role of microorganisms in infectious diseases, the nature of microbial infections indifferent body systems, infection control, immunity and mechanisms of host resistance, common vaccines, the mode of action of antibiotics, and the development of drug resistance. The importance of the human microbiome in health and disease will also be taught.

Learning outcomes Upon completion of this unit students should be able to:

  1. Describe and explain the patho-physiological change and clinical manifestation of disorders of water and electrolyte metabolism, disorders of acid-base balance, shock, disorders of coagulation and anticoagulation balance, ischemia-reperfusion injury, pulmonary pathophysiology, cardiovascular dysfunction, hepatic pathophysiology and renal dysfunction.
  2. Describe and differentiate the common types of microorganisms.
  3. Explain and evaluate the structure, physiology and lifecycles of viruses, bacteria, fungi and protozoa, and the roles of microorganisms in physiology and human disease.
  4. Demonstrate knowledge of the relationship between microorganisms and human immunity, principles of infection control.
  5. Explain the modes of action of commonly used antibiotics, vaccines and how microorganisms become resistant to drugs.
Unit requirement To successfully complete the unit, students must: attend 80% of all the lectures and tutorial classes, attempt all assessment tasks including formative and summative assessments and achieve at least 50% of the total marks, and achieve a mark of at least 40% in the final examination.
Assessment Assessment 1: Pathophysiology Quiz (25%)

Assessment 2: Microbiology Essay (25%)

Assessment 3: Final examination (50%)

Prescribed text * The prescribed and recommended readings are subject to annual review.

Porth, C. (2014). Essentials of pathophysiology: Concept of altered health states (4th ed.). Philadelphia, PA: Lippincott Williams & Wilkins.

Recommended readings McCance, K. L., & Huether, S. U. (2014). Pathophysiology: The biological basis for disease in adults and children (7th ed.). St. Louis, Mo: Elsevier/Mosby.

Murray, P. R. et al. (2016). Medical Microbiology (8th ed.). Philadelphia, PA: Elsevier.

Willey, J. M. et al. (2017). Prescott’s Microbiology (10th ed.). New York, NY: McGraw-Hill.